However, there was no longterm toxicological assessment for nk603, or for roundup. Controversy over study with genetically engineered maize. The gm maize alone was tested on three groups at 11%, 22% and 33% of the total diet. Nov 28, 2012 efsa concludes that the currently available evidence does not impact on the ongoing re. Date added to website 25th june 2014 gmfree cymru welcomes the republication of this important study, which was retracted last year from fct journal following a coordinated and vicious campaign of vilification and dafamation directed at prof gilleseric seralini and his fellow researchers by the assembled ranks of the gm industry and its acolytes. The most pronounced metabolome differences between nk603 and its isogenic counterpart consisted of an increase in polyamines including nacetylcadaverine 2. The data are inconclusive, therefore the claim ie, conclusion that roundup ready maize nk603 andor the roundup herbicide have a link to cancer is unreliable it is the entire paper, with the claim that there is a definitive link between gmo and cancer that is being retracted. I desire that seralini s response to criticism, published in a mainstream journal, and the discussion linked to showing how the efsa, in spite of its attack on seralini, has indirectly validated his protocols which, from my understanding, comes not just from a random source, but from a source connected to seralini and some of the other. The nk603 maize sprayed with roundup separates from the unsprayed nk603 maize on the second component vertical axis, percentage of explained variance of 16. How to combine pdf files into one document lifewire.
First published by food and chemical toxicology in september 2012, the article presented a twoyear feeding study in rats, and reported an increase in tumors among rats fed genetically modified corn and the herbicide roundup. The nk603 data are in a pdf format preventing an easy statistical reanalysis. Nk603 produces the cspb protein, derived from bacillus subtilis, which provides reduced yield loss under waterlimited conditions compared to conventional maize. Nk603 contains two copies of the cp4epsps gene controlled by one of two promoters. The european food safety authority efsa and the german federal institute for risk assessment bfr published their opinion on a french study that. Pdf a paper reporting findings relevant to safety of the genetically modified gm maize nk603 and the herbicide roundup seralini et al. Moreover, we demonstrated in several studies 810 that roundup is far more toxic than glyphosate because of noninert adjuvants. Indeed, the expression data reveal a much higher content of these enzymes compared to the. The efsa had previously assessed nk603, and glyphosate, the declared active principle of roundup, as safe on the basis of regulatory data, which they never fully published. When the paper by seralini and his team 1 was published on 19th september 2012, showing that both gm maize nk603 and roundup herbicide had dramatic negative effects on the health of rats during a twoyear feeding trial, efsa should of course have welcomed the new research, put an instant moratorium on all pending gmo applications in the. Nk603 rat glyphosatebased herbicides endocrine disrupting effects abstract the health effects of a rounduptolerant genetically modi. Maize mon 87427 x mon 87460 x mon 89034 x mir162 x. Scientists and regulatory agencies subsequently concluded that the studys design was flawed. Monsanto published the results of its trial in 2004, 2 the same year that the maize was authorized in the eu.
The seralini paper has caused much uproar in kenya where the ministry of public health, without consulting local biotech experts, seems to have unwittingly fallen into the complex world of antibiotech groups who boast of the ban as a major propaganda breakthrough. The health effects of a rounduptolerant nk603 genetically modified gm maize from 11% in the. Long term toxicity of a roundup herbicide and a roundup. Glyphosate tolerant genetically modified gm maize nk603 was assessed as. One field of nk603 was treated with r at 3 l ha 1 weather max, 540 gl of glyphosate, epa reg. Control samples had the most distinct proteome and metabolome pro files as observed in pca plots. Corn cobs were harvested when the moisturecontent was less than 30% and were dried at a temperature below 30c.
This oftenupdated app combines a large number of pdf files from your android device, as well as many other useful features. Mon 863, mon 810 and nk603 assessment of quality and response to technical issues synopsis. Please, select more pdf files by clicking again on select pdf files. Summary the biotech industry has launched an extensive offensive to discredit the study published last september by a team of french researchers suggesting serious concerns about the long term health impact of monsantos nk603 maize and the roundup herbicide it has been genetically engineered. They defended their choice of spraguedawley rats by claiming that it is important to use a type. Conflicts of interests, confidentiality and censorship in. If they had been faulty, that would have been good grounds for the retraction.
The study used 200 rats divided into ten groups, each of ten males and ten females. All results were hormone and sex dependent, and the pathological pro files were comparable. A paper reporting findings relevant to safety of the genetically modified gm maize nk603 and the herbicide roundup seralini et al. Wallace hayes, has decided to retract the study by the team of prof gilleseric seralini, which found that rats fed a monsanto genetically modified gm maize nk603 and tiny amounts of the roundup herbicide it is grown with suffered severe toxic effects, including kidney and. That article was subsequently retracted by the journal publisher, followed by an explanatory note from. Introduction the safety of gm food and monsantos herbicide roundup has once more been put into question following the study published on 19 september in the us scientific journal food and chemical toxicology assessing the toxicity of monsantos gm rounduptolerant maize nk603, roundup herbicide and the two combined, on rats1. Gilleseric seralini c with dr joel spiroux r and mep corinne lepage afp photokenzo tribouillardwith just a few articles, these journalists set off a media firestorm that renewed concerns about gm foods and forced the mainstream scientific establishment onto the defensive. The editor of the journal food and chemical toxicology fct, dr a.
Despite some limitations in the free edition of this app, including a maximum file size of 2. A presentation of ansess opinion following its analysis. Click add files and select the files you want to include in your pdf. Efsa concludes that the currently available evidence does not impact on the ongoing re. However, anses emphasises the small number of published studies dealing with the potential longterm effects of the consumption of gmos in association with pesticides and recommends undertaking research into these issues. Nk603 is the identifying number for a herbicidetolerant roundup ready gm corn event developed by monsanto and approved in canada in 2001. Jun 24, 2014 one field of nk603 was treated with r at 3 lha. Hyping the reputation of a scientist or a team is a serious misdemeanor when it helps to spread. From thesethree cultivations of maize, laboratory rat chow was made based on the. Reactions to republication of landmark seralini gmo study. The seralini study rat feeding study for 2 years fed gm maize nk603, roundup ready unsprayed 11%, 22%, 33% sprayed with roundup 11%, 22%, 33% roundup in drinking water 3 doses controls fed nongm isoline 10 animals in each group whole setup for males and females mortality fig. For maize mon 87427 x mon 89034 x nk603 treated with glyphosate.
The commission made its request to efsa after the publication of the 2012 seralini study, which showed that feeding a monsanto gm maize, nk603, and tiny amounts of roundup herbicide to rats over a longterm 2year period had serious toxic effects, including organ damage and increased tumour rates. The efsa has since published monsantos safety data on nk603 maize, but not on glyphosate. They responded to the charge that their sample was too small by noting that 90day feeding trials use only 10 animals per male and female group seralini et al. Basic functionality is available without a fee, while an adfree experience can be had with inapp purchases. After several months of consumption of an rtolerant soy, the liver and pancreas of mice were affected, as highlighted by disturbances in subnuclear structure malatesta et. Data used for the functional analysis were selected at the statistical cutoff values of p 1. I desire that seralinis response to criticism, published in a mainstream journal, and the discussion linked to showing how the efsa, in spite of its attack on seralini, has indirectly validated his protocols which, from my understanding, comes not just from a random source, but from a source connected to seralini and some of the other.
Maize mon 87427 x mon 87460 x mon 89034 x mir162 x nk603. Merge pdf files combine pdfs in the order you want with the easiest pdf merger available. That fact highlights how little funding goes to gmo safety studies. Scienceafrica journalist european food safety authority. John fagan1, terje traavik 2,3 and thomas bohn2 abstract a paper reporting findings relevant to safety of the genetically modified gm maize nk603 and the herbicide roundup seralini et al. You can merge pdfs or a mix of pdf documents and other files. The reason for crossing nk603 with mon 87427 was to increase the content of epsps enzymes that confer resistance to glyphosate. Public perception on labeling of genetically modified gm. Mon 87427 x mon 89034 x nk603 not treated with glyphosate, statistically significant differences with the nongm comparator were identified for 42 grain endpoints. After several months of consumption of an rtolerant soy, the liver and pancreas of mice were affected, as highlighted by disturbances in subnuclear structure malatesta et al 2008a. Seralinis team and their methodology were found to be honest and sound.
How to merge pdfs and combine pdf files adobe acrobat dc. To change the order of your pdfs, drag and drop the files as you want. Gmo myths and truths seralini study attacked by progm. The most significant results of the extended study by seralini and colleagues are signs of toxicity for all treatments gm maize sprayed and unsprayed with roundup and rounduponly treatments.
Wallace hayes, has decided to retract the study by the team of prof gilleseric seralini, which found that rats fed a monsanto genetically modified gm maize nk603 and tiny amounts of the roundup herbicide it is grown with suffered severe toxic effects, including kidney and liver damage and increased rates of. Longterm toxicity of a roundup herbicide and a rounduptolerant genetically modified maize, by gilleseric seralini, et. Seralini found that gm maize and residues of the roundup herbicide sprayed on the crop were toxic to the laboratory rats and their findings are now validated by this republication in a. Controversy over study with genetically engineered maize and roundup. Dec 19, 2016 the nk603 maize sprayed with roundup separates from the unsprayed nk603 maize on the second component vertical axis, percentage of explained variance of 16. Authors aimed at assessing the longterm toxicity of the commercial formulation of roundup herbicide and the maize line nk603 monsanto corp. A presentation of ansess opinion following its analysis of. Levels of carbohydrates even fell under equivalence category iii and differences in calcium under category iv. The seralini study an attack on independent research. Transcriptome and metabolome analysis of liver and. Seralinis 2012 study1 tested the longterm effects of monsantos gm nk603 maize, which is engineered to survive being sprayed with roundup herbicide, and roundup.
Journal retraction of seralini study is illicit, unscientific. Proof that efsa used double standards to attack seralini. The pathway analysis was done using the thomson reuters metacore analytical suite andor the nih. Republication of retracted seralini study gm free cymru. Click, drag, and drop to reorder files or press delete to remove any content you dont want. Seralini and coauthors replied to their critics in the march 20 issue of fct. Prior publications by seralini and colleagues in both the pesticide and gm crops arenas have.